
Yes you can kill every MHW boss again and again, all you need to do is to talk to Alma.
Guide
1. Find Alma and talk with her.
- You can always find her in base camps next to your tent.
2. In Quest Menu tab click on the Post/Join Quest.
3. Select Optional Quests and choose the monster you want to fight.
4. Click on the Accept & Depart to start the quest.